A recent global report released by the World Health Organization (WHO) reveals that nearly four out of every ten new cancer cases throughout the world could be avoided through changes in behavior, enhanced public policies, and effective public health initiatives.
The findings, which coincide with World Cancer Day celebrated on February 4, 2026, are derived from a study published in Nature Medicine, encompassing data from 185 nations and focusing on 36 different cancer types.
According to the report, around 37% of the 18.7 million new cancer cases noted in 2022 were linked to adjustable risk factors such as tobacco consumption, infections, and environmental factors related to lifestyle.
Maria Neira, the Director of Environment, Climate Change and Health at WHO, emphasized, "The science is conclusive. A significant proportion of cancers, particularly those related to tobacco use, infectious diseases, and harmful environments, can be prevented."
The study identified tobacco as the most significant preventable cause of cancer, contributing to about 15% of new global cases. Additionally, infectious agents like human papillomavirus (HPV) and Helicobacter pylori account for approximately 10% of cancer cases worldwide.
Elisabete Weiderpass, Director of the International Agency for Research on Cancer, stated, "Cancers associated with smoking and infections continue to have a devastating impact. Prevention is not only achievable, but it also must be a priority."
Cervical cancer is highlighted in the report as a prime example of a preventable disease, primarily caused by HPV, for which safe and effective vaccines exist.
Likewise, cancers associated with Helicobacter pylori infections can also be prevented or managed through improved sanitation, early detection, and medical screening, which were notably highlighted in the report's findings.
"We are at a pivotal moment where public health initiatives such as HPV vaccination programs, tobacco control policies, and healthier environmental strategies could save millions of lives," Weiderpass added.
The analysis also indicated significant disparities in the burden of preventable cancers across different regions and between genders. For males, approximately 45% of cancer cases could be attributed to adjustable risk factors, while roughly 30% of cases for females were linked to the same.
Distinct patterns were observed among regions. East Asia, Latin America, North Africa, and West Asia displayed unique trends of preventable cancer risks tied to lifestyle choices, environmental exposures, and access to preventive healthcare.
Neira noted, "These variations point to differences in lifestyles, environmental exposures, and the availability of preventive healthcare. Thus, tailored and locally specific strategies are essential."
The WHO is calling on governments and healthcare systems to enhance successful prevention strategies, including raising tobacco taxes, instituting public smoking bans, promoting vaccination programs, and improving air quality.
"We need to redirect our focus upstream," Neira advised. "Investing in prevention not only preserves lives but also lessens long-term healthcare costs and strengthens robust health systems."
The report concludes that, despite cancer being a significant global health concern, nearly 40% of cases could potentially be avoided through coordinated public health strategies, committed political engagement, and ongoing community involvement.

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